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Catching Strep: Cost-Comparison of Peri-Natal Screening Assays for Goup B Streptococcus

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Please use this identifier to cite or link to this item: http://hdl.handle.net/1928/9751

Catching Strep: Cost-Comparison of Peri-Natal Screening Assays for Goup B Streptococcus

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Title: Catching Strep: Cost-Comparison of Peri-Natal Screening Assays for Goup B Streptococcus
Author: Dempsey, Bradley; Leeman, Lawrence; Phelan, Sharon; Young, Steven
Subject(s): Group B Streptococcus
Streptococcus
Peri-Natal Screening
Abstract: CATCHING STREP: COST-COMPARISON OF PERINATAL SCREENING ASSAYS FOR GROUP B STREPTOCOCCUS. BG Dempsey, L Leeman, S Phelan, and S Young, University of New Mexico School of Medicine, Albuquerque, NM Purpose: To determine how the implementation of a rapid polymerase chain reaction (PCR) –based assay for Group B Streptococcus (GBS) affects the treatment and management of women presenting to the hospital, in labor with an unknown GBS culture status. Methods: We performed a retrospective chart review of women presenting in labor with an unknown GBS culture status to a large university –based hospital. We compared two groups of women: 1. Women who presented prior to the implementation of the Rapid PCR culture who were cultured using traditional methods; 2. Women who presented after the Rapid PCR GBS culture was implemented as a standard of care. We analyzed variables such as length of hospital stay, administration of prophylactic antibiotics against GBS, GBS-associated laboratory testing, and patient demographics. Results: The implementation of the Rapid PCR GBS culture was associated with a higher median cost of hospital stay compared to the traditional GBS culture method, while resulting in less extended hospital stays due to concerns for neonatal GBS infections. Conclusion: The implementation of Rapid PCR GBS cultures for women presenting in labor with an unknown GBS status does not correlate with cost-savings or decreased length of post-partum hospital stay despite being associated with a decrease in the number of infants with a prolonged hospital stay secondary to GBS concerns. Supported in part by the University of New Mexico (UNM) School of Medicine.
Date: 2009-08-18
URI: http://hdl.handle.net/1928/9751

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