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A comparison of dental practitioners' knowledge of the adverse oral effects of pharmaceuticals; specifically, low-dose methotrexate, diltiazem, cyclosporine, istretinoin, and lisinopril

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Please use this identifier to cite or link to this item: http://hdl.handle.net/1928/9320

A comparison of dental practitioners' knowledge of the adverse oral effects of pharmaceuticals; specifically, low-dose methotrexate, diltiazem, cyclosporine, istretinoin, and lisinopril

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Title: A comparison of dental practitioners' knowledge of the adverse oral effects of pharmaceuticals; specifically, low-dose methotrexate, diltiazem, cyclosporine, istretinoin, and lisinopril
Author: Van Witzenburg, Melissa
Advisor(s): Nathe, Christine
Committee Member(s): Sanchez-Dils, Elaine
Plese, Melissa
Department: Dental Hygiene
Subject(s): low-dose methotrexate
diltiazem
cyclosporine
isotretinoin
lisinopril
mucositis
xerostomia
angular chelitis
gingival hypertrophy
LC Subject(s): Dentistry--Practice--New Mexico.
Physician practice patterns--New Mexico.
Dental care--New Mexico--Evaluation.
Dental surveys--New Mexico.
Drug monitoring--New Mexico.
Drugs--Side effects.
Mouth--Effect of drugs on.
Teeth--Effect of drugs on.
Drug interactions.
Degree Level: Masters
Abstract: There are more than 15, 000 approved prescription and over-the-counter drugs, diagnostics, and intravenous supplementation products in the United States. Due to the increased number of patients using medications it is important that dental providers are aware of common adverse oral complications. The most commonly seen adverse oral effects of medications are xerostomia, gingival hypertrophy, angular cheilitis, and mucositis. The purpose of this study was to examine dental providers, “subjects” knowledge of adverse oral effects of low-dose methotrexate, diltiazem, cyclosporine, isotretinoin, and lisinopril. Four of the five hypotheses tested demonstrated high P-values, therefore; they were consistent with the null hypothesis. However, these four hypotheses yielded insight into areas of further study. When evaluating the number of continuing education hours that subjects participate in annually compared to their responses on the survey, a statistically significant difference was demonstrated. A P-value of 0.022 was obtained, with subjects participating in 26+ hours of continuing education scoring an average of 0.629 higher than those who participate in 25 or fewer hours of continuing education annually. Data suggests that further studies are needed to evaluate where students are instructed on adverse oral effects in an educational setting and how much time is spent on the subject matter. Other areas of further investigation would include a study of established dental providers and how could their attainment of knowledge improve. Most importantly this data highlights a deficiency in information regarding adverse oral effects. It is crucial that this topic be researched further and dental providers are educated on this subject matter to ensure the highest quality of care to dental patients.
Graduation Date: May 2009
URI: http://hdl.handle.net/1928/9320

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