LoboVault Home
 

Infection Rates following Peri-Operative Prophylactic Antibiotics vs. Post-Operative Extended Regimen Prophylactic Antibiotics in Surgical Management of Mandibular Fractures

LoboVault

Please use this identifier to cite or link to this item: http://hdl.handle.net/1928/6871

Infection Rates following Peri-Operative Prophylactic Antibiotics vs. Post-Operative Extended Regimen Prophylactic Antibiotics in Surgical Management of Mandibular Fractures

Show simple item record

dc.contributor.author Lovato, Christine
dc.contributor.author Wagner, Jon
dc.date.accessioned 2008-08-22T15:22:36Z
dc.date.available 2008-08-22T15:22:36Z
dc.date.issued 2008-08-22T15:22:36Z
dc.identifier.uri http://hdl.handle.net/1928/6871
dc.description.abstract Purpose: To determine whether or not an extended regimen of prophylactic antibiotics following either open or closed reduction of mandibular fractures is beneficial in lowering the rate of infection in post-operative patients. Patients and Methods: This study is a retrospective chart review of 150 patients treated operatively for both complicated and uncomplicated mandibular fractures at UNM Health Sciences Center in Albuquerque, NM, between January 1st, 2000 and June 12, 2007. Treatment modalities used were closed reduction with maxillomandibular fixation or open reduction and internal fixation with either wire osteosynthesis or rigid internal fixation. Patients fell into one of two groups: the first group received antibiotics peri-operatively, which consisted of no more than 24 hours of antibiotics in the postoperative period and the second group received extended regimen antibiotics, which consisted of anywhere from 24 hours to 10 days of antibiotics in the postoperative period. 75 patients were included in each group. The type of antibiotic prescribed was at the discretion of the operating surgeon. This study was done using an intention-to-treat analysis. Postoperative infection was diagnosed either subjectively or objectively by the clinician evaluating the patient at follow-up appointments. Results: In the extended antibiotic group, 8 out of 75 subjects (10.67 percent) developed infection. In the peri-operative antibiotic group, 10 out of 75 subjects (13.33 percent) developed infection. Statistical analysis using chi-square distribution showed that this difference in proportions was not significant (Chi-square=0.06, p=0.8). Conclusions: This study found that the use of post-operative prophylactic antibiotics does not have a statistically significant effect on post-operative infection rates in surgical management of complicated or uncomplicated mandibular fractures. en_US
dc.language.iso en_US en_US
dc.subject Prophylactic Antibiotics en_US
dc.subject Mandibular Fractures en_US
dc.title Infection Rates following Peri-Operative Prophylactic Antibiotics vs. Post-Operative Extended Regimen Prophylactic Antibiotics in Surgical Management of Mandibular Fractures en_US
dc.type Article en_US


Files in this item

Files Size Format View
Lovato Researchpaperfinal.pdf 65.15Kb PDF View/Open

This item appears in the following Collection(s)

Show simple item record

UNM Libraries

Search LoboVault


Advanced Search

Browse

My Account