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Chronic Endometritis Revisited: A Review of the Pathology and Clinical Findings

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Please use this identifier to cite or link to this item: http://hdl.handle.net/1928/6822

Chronic Endometritis Revisited: A Review of the Pathology and Clinical Findings

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dc.contributor.author Hagerty, Kori
dc.contributor.author Smith, Matthew
dc.contributor.author Bocklage, Therese
dc.date.accessioned 2008-07-30T20:22:34Z
dc.date.available 2008-07-30T20:22:34Z
dc.date.issued 2008-07-30T20:22:34Z
dc.identifier.uri http://hdl.handle.net/1928/6822
dc.description.abstract Background: Chronic endometritis is a histopathologic diagnosis characterized by endometrial inflammation rich in plasma cells. Through examination of this disease, we hope to further elucidate the meaning of its diagnosis and whether or not it should be more carefully considered when examining specimens. Methods: A retrospective chart and slide review was conducted that focused on the collection of clinical data and the examination and description of previous tissue samples from endometrial biopsies. A total of 94 chronic endometritis cases and 99 controls were identified. All statistical analyses were conducted using SAS version 9.1. Results: Women with chronic endometritis were more likely to be within 41-50 year of age (39/95, 41.1%), with 65.3% of cases in the 31-40 and 41-50 age categories (23/95, 39/95). They were also more likely to be perimenopausal (42/92, P-value 0.0015) and multiparous (79.1%, P-value 0.1358). Additionally, hormone use was found to be significantly associated with endometritis (P-value 0.0299). No specific symptoms were found to correlate with chronic endometritis. Our study confirmed that the presence of lymphocytes (P-value <0.0001), neutrophils (P-value 0.0029), and macrophages (P-value 0.0048) are associated with endometritis along with epithelial change/metaplasia (P-value 0.0595). Discussion: Our study has helped to better understand the demographics of endometritis and its clinical presentation; but as always, more studies are needed to further elucidate the implications of this disease for women. en_US
dc.language.iso en_US en_US
dc.subject Chronic Endometritis en_US
dc.subject Pathology en_US
dc.title Chronic Endometritis Revisited: A Review of the Pathology and Clinical Findings en_US
dc.type Article en_US


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