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Falls, frailty and osteoporosis in the elderly: a public health problem


Please use this identifier to cite or link to this item: http://hdl.handle.net/1928/1905

Falls, frailty and osteoporosis in the elderly: a public health problem

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Title: Falls, frailty and osteoporosis in the elderly: a public health problem
Author: Vellas BJ, BJ; Nourhashemi F, F; Rolland Y, Y; Lauque S, S; Ousset PJ, PJ; Moulias S, S; Gillette-Guyonnet, S; Andrieu S, S; Fontan B, B; Adoue D, D; Lafont CH, CH; Baumgartner RN, RN; Garry PJ, PJ; Albarede JL, LJ
Subject(s): osteoporosis
Abstract: INTRODUCTION: Elderly people can be subdivided into three groups: healthy elderly persons (65-70% of the population), elderly subjects with diseases (about 5%) and frail old people. Frailty represents "age-related physiologic vulnerability resulting from impaired homeotasic stock and a reduced capacity of the organism to withstand stress". It could lead elderly subjects to pathological, barely reversible, ageing. CURRENT KNOWLEDGE AND KEY POINTS: One of the main objective of geriatricians is to develop useful screening tools to identify people at high risk, thus allowing them to benefit from preventive interventions as early as possible. It has been suggested that the decline in homeostatic stock involves numerous physiological systems. Those at the core of frailty would be neuromuscular changes resulting in sarcopenia, neuroendocrine dysregulation, and immune disorders. A recent study has shown that increased levels of interleukin 6 is a risk factor for frailty. FUTURE PROSPECTS AND PROJECTS: Work in progress aimed at identification of at-risk patients should: lead to early detection; draw attention on underestimated fields such as the nutritional status, sarcopenia, or gait disorders; promote the development of the standardized gerontological evaluation in order to identify the different components of frailty; and promote the development of non-pharmacological programmes including physical training, nutritional managing, and optimal social life.
Date: 2006-09-18
Publisher: Vellas, BJ - La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne
Citation: 2000 Jul;21(7):608-13
Description: For full-text go to PubMed, ID: 10942977
URI: http://hdl.handle.net/1928/1905

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